Supplementing naturally occurring peptides and nutrients helps support your body’s mitochondria. I’m joined by naturopathic doctor, Amber Krogsrud, to talk about how she uses peptides to improve both her and her patient’s overall health.
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About Amber Krogsrud
Dr. Amber Krogsrud is a naturopathic doctor who focuses on holistic hormone health. She has a Bachelor’s degree in Biology with a Minor in Chemistry from NDSU in Fargo, North Dakota. Prior to her undergraduate studies, she worked in a chiropractic clinic and discovered the beauty of natural medicine. She also developed a passion for nutrition and began pursuing a career that viewed health as a holistic lifestyle involving food as nutrition.
To convert this passion to a career, Dr. Amber completed a four-year medical degree at the prestigious Bastyr University in San Diego, California. during her clinical years at BUC, Dr. Amber interned at an alternative health access campaign (AHAC) in Seattle, a clinic that focuses on bringing naturopathic treatment to at-risk youth and homeless adults.
As a medical student, Dr. Amber was handpicked as a member of the naturopathic medical student association (NMSA) as the professional development chair and was gifted the prestigious Bragg’s Foundation scholarship award.
What You Need to Know About the Mitochondria
Dr. Amber joins me today to talk about peptides, but before we can talk about them, we need to go back to basics. First, we’re talking about mitochondria: what it is and what role it plays in our bodies.
She explains how we can support our mitochondria from a cellular level, by supplementing our diets, physical level with diet and exercise, and an external level with outside assistance. Amber shares some tips for how you can improve your diet for optimal health. She says that fasting, or intermittent fasting, is one of the most beneficial ways you can eat.
Amber uses a red light to improve her mitochondria function. The additional benefits of the red light she uses are hair growth and collagen repair.
The final bit of the mitochondria puzzle is the supplements you can take to support it. Amber loves NAD (Nicotinamide Adenine Dinucleotide), a coenzyme that your body naturally produces. She explains the different ways you can supplement NAD in your wellness routine.
How to Use Peptides to Support Your Health
Peptides are naturally occurring biological molecules that are found in all living organisms and have a key function in all biological activity. They’re chains of amino acids that form the basis of almost everything our body does, including producing collagen in the skin.
Amber explains the different types of peptides our bodies use to keep them running in good condition. Some peptides are more commonly found in animal products, so vegans and vegetarians may need to supplement these.
An interesting study about CoQ10, a peptide that helps your cells generate energy, found that women with breast cancer have lower levels of this peptide. Amber explains what these findings show and how these results have shown up in her own medical practice.
Overall, peptides are a fantastic addition to your health. They can promote weight loss, improve collagen production, and benefit your skin and hair health. As Amber says, there really is a peptide for everything!
The average person will want to use peptides to help encourage their body to produce more themselves. You can expect a monthly investment between $300-400, depending on the peptide combination you use.
- NAD is a nutrient you can supplement that helps support your mitochondria. It increases your energy levels and helps clear brain fog. [18:00]
- You can use peptides in combination with diet and lifestyle changes to lose weight and improve your overall health [30:20]
- The average cost for including peptides in your health and wellness routine is $300 – $400 per month. [38:37]
“The overall effects of the NAD is to help the mitochondria. If they’re really in a depleted state, they might actually feel a little more tired; most people feel energized, but it’s hard to know how someone will respond to their first NAD IV.” [20:39]
“There’s literally a peptide for most everything. There’s a peptide for everything! But they work through cellular signaling.” [28:26]
“For the average person, what we want to do is refine their body’s ability to make more peptides themselves.” [32:57]
In This Episode
- What the role of mitochondria is in our bodies [3:15]
- What lifestyle changes you can make to support your mitochondria [5:30]
- The benefits of red light therapy [7:20]
- Why breast cancer patients tend to have lower levels of CoQ10 [11:41]
- Dr. Krogsrud’s top peptide recommendations [29:27]
Links & Resources
Join PeptideRX: Recreate Your Health, Dr. Amber’s Facebook Group
Find Dr. Amber Krogsrud Online
Follow Dr. Amber Krogsrud on Instagram | Facebook | Twitter | YouTube | Pinterest
Get your copy of the Your Longevity Blueprint book and claim your bonuses here
Follow Dr. Stephanie Gray on Facebook | Instagram | Youtube | Twitter | LinkedIn
Integrative Health and Hormone Clinic
Podcast Production by the team at Counterweight Creative
5 Supplements Myths Pt 1 w/ Tom Houle
Anti-Aging Tips for the Skin with Rachel Varga
Intermittent Fasting Truths with Cynthia Thurlow
Dr. Amber Krogsrud 0:03
causing that kind of micro trauma to the area. We know that that compounds the results of peptides when you combine the micro needling plus the peptides they get much better results so people can apply the peptides topically. They're more effective when done in a topical way with micro needling.
Dr. Stephanie Gray 0:24
Welcome to the longevity blueprint podcast, I'm your host, Dr. Stephanie gray. My number one goal with the show is to help you discover your personalized plan to build your dream health and live a longer, happier, truly healthier life. You're about to hear from Dr. Amber Krogsrud.
Today's topic is novel peptide therapy options to boost mitochondrial health for brain power, body composition and even hair growth. And we're going to get into an ad Welcome to another episode of the longevity blueprint podcast today we have on our show Dr. Amber Craig's rude doctor Amber is a licensed naturopathic doctor at Metro MD Institute of Regenerative Medicine in Los Angeles, California. She's trained in regenerative medicine, detoxification protocols, hormone testing and treatment, bioidentical hormone therapy, peptide therapy and IV nutrient therapy. She also has a practice in Redondo Beach, California, where she specializes in bioidentical hormones and peptide therapy. Dr. Amber is also a member of the International peptide society and has completed the peptide therapy certification training through the American Academy of anti aging medicine. So welcome, Dr. croxford.
Dr. Amber Krogsrud 1:32
Thank you. It's so good to be here. We're kindred spirits, because we both work with woman work with hormones and peptides. There's just a whole new exciting topic that we get to share with the world today.
Dr. Stephanie Gray 1:45
They absolutely are. I can't I can't wait to get to that. But I think let's open talking about mitochondria. So I recently had dr. Terry walls on as a guest. She's a colleague and friend also from Iowa. And we talked about her walls protocol that she strategically created to fuel her mind condra with food Above and Beyond Diet today, I want to get into what nutrients even supplements you believe are best for fueling or mitochondria. But let's let me first start by asking you what our mitochondria are and what they do.
Dr. Amber Krogsrud 2:14
Yeah, so it's really interesting. I have this conversation with a lot of my patients bring up the word mitochondria. And a lot of times I kind of get like a blank look like what are the mitochondria, going back to the you know, eighth grade biology of what they are, but they're really the example I like to give is, they're the powerhouse of the cell.
So I live in LA, and we have, you know, multiple places where we generate power here. But if, if those were at all, discontinue producing power at this very moment, the entire city of La which is like a cell would not function appropriately, all the other things that would happen, I wouldn't be able to charge my laptop or my phone or run the dishwasher all those things and so on. similar thing happens in our mitochondria. They are the powerhouse of the cell. They're making ATP energy for the cell to do all of its functions to protect itself. So it really has the mitochondria have a dual function, they protect the cell from damage, and they also produce energy.
And so when they're so focused on one task, they're maybe less efficient at the others, it's really important to have this robust energy production of ATP so that all of our cells are functioning appropriately. And, you know, what we see is as we age, and as there's more oxidative stress, and our mitochondria quit working as effectively producing that ATP, to fuel the cell to do its work. You know, we end up experiencing things like lethargy, brain fog fatigue, because we know that the two cells that have the most mitochondria are the next ourselves, so the brain a lot of nerve tissue and the muscles, right, which is why in a lot of these conditions like Ms and ALS, you know, even like Fibromyalgia or chronic pain where we can trace that back to a mitochondrial dysfunction that's happening even on autism.
There's a lot of literature out there right now and some clinics that specialize in autism and they're using a mitochondrial based approach. Because we're identifying wow, you know, when we're having nerve conduction, nerve issues, cognitive things, maybe it's related to mitochondria. And we're finding that it is so yeah, I think it's, it's not really something that most people probably wake up thinking about how can I help my mitochondria today? But the more that I learned about it, and the more that you know, as practitioners we we learned about it, we knew the world to this lens, and wow, how we how can we support these systems and our Patients educate them on how to support their mitochondria producing energy, you know, really protecting and preventing illness through a mitochondrial lens.
Dr. Stephanie Gray 5:11
That's awesome. So how do we do that? So, so how do we support our mitochondria? Maybe let's start from a lifestyle standpoint, and then we'll get into nutrients and supplements.
Dr. Amber Krogsrud 5:21
Yeah, so there's a lot of things that can really support mitochondrial function. One of the things that has been researched is fasting, that can actually be really supportive. So intermittent fasting, doing a couple day fasts can kind of recalibrate those mitochondria and they get really efficient ourselves become, you know, more efficient in that state.
One of the things that I like to do lifestyle wise is a red light. So I actually have one sitting right by me here that altern not working We know that red light that wavelength does is it can actually help to activate the mitochondria to work more effectively. Which is really pretty cool. If you think about light as a, you know, bio charger of ourselves.
There's many other things, you know, looking at diet, looking at antioxidants, really fortifying the diet, or supplementation if we can't get it through diet with things that are going to protect the mitochondria from damage, because we have DNA in our mitochondria too, right? We learned about that in in med school. And not only is a nucleus of mitochondria, but the nucleus of DNA where the mitochondria does as well. Yeah, so it just becomes really important to add in all those antioxidants, and we can talk about some of those antioxidants.
Dr. Stephanie Gray 6:55
Let's go back to red light therapy because I'm kind of a podcast junkie. I listen. Do a lot of podcasts. And recently I listened to one that talked a lot about red light therapy. And so I am again not an expert, I hope to bring on an expert one day to assess that, but tell us how you utilize your so when you say you turn that on when you're working, like how many minutes? How many times a day? How are you utilizing that? And how do you feel that you've benefited from it?
Dr. Amber Krogsrud 7:21
Great question. I love talking and sharing with this with my patients and I think even better to share it out to the masses on the podcast. So I use mine for about 15 to 20 minutes a day. There's diminishing effects. Using it much longer than that using it for like two hours is probably not gonna, you know, produce a massively, a massive effect, but it's really a small threshold. I don't know if you've seen Have you seen those caps that you can get for grow?
Dr. Stephanie Gray 7:53
Yeah, I can't buy a larger machine. Yeah.
Dr. Amber Krogsrud 7:57
Yeah. Yeah. So You know, I use my red light for hair regrowth and for skin in a similar way that they kept us I just, you know, lay my head against it, and you know, maybe look or something. So in the end, then I'll do micro needling on my skin and I'll use it to help regenerate the collagen my skin so and then what also do is kind of lean my, my lower back because I'll just get, you know, kind of muscle tension from exercising or sitting, working at a desk a lot. And I actually find that it does because it supports mitochondria. It can help with muscle repair, post exercise or just sitting a lot so it can help with muscle tension that way, but it's Yeah, I want to see your experience.
Dr. Stephanie Gray 8:46
Well, not much yet. But I think that's the main application that many individuals are familiar with recovery repair, but I'm more fascinated. So I have used it for skin or for hair. regrowth stop some hair loss, but I have Don't use it on my face like for my skin for collagen. So I look forward to I'd like to purchase a home machine that looks very portable, very, very portable. Yes, super
Dr. Amber Krogsrud 9:10
easy to. Yeah, I, you know, you could travel with it if you really want to.
Dr. Stephanie Gray 9:15
Cool. Thank you for that tip. I didn't really think of that as supporting mitochondria health, but obviously it makes sense that it would. So let's talk about the antioxidants you are mentioning. So let's go into some of those. What are your maybe top few
Dr. Amber Krogsrud 9:32
certainly recommend. So we'll walk through a few. The one that's really commonly known because of statin drugs is Koki 10. So that's the one co q 10 is coenzyme. It carries electrons into the electron transport chain, which is what's happening in the mitochondria to make that ATP. So it's a really important piece for the process of generating energy in the cell. And when we don't have enough coke eaten ourselves our mitochondria is more susceptible to damage oxidative stress as Super protective so I like to watch especially if you're on a stem drug but even not adding in some cokie 10s it's not really something that's found in a ton of foods you
Dr. Stephanie Gray 10:21
Dr. Amber Krogsrud 10:22
it's really something that you have to supplement with.
And then a couple of the other ones, I love alpha alpha lipoic acid, and then acetyl l carnitine. And acetyl l carnitine. is one that's touted as you know, the fat burning nutrient and is found in meats. For someone who's vegan, they're probably not going to get a ton of l carnitine. in their diet, so that one might be better supplemented for them. And, you know, we learned this in medical school too. What l carnitine does is it takes those fatty acids And our adipose tissue, shuttles them into the mitochondria to be burned for energy,
Dr. Stephanie Gray 11:06
like coal in a train is how I described that to my patients it shovels that coal, and now that a lot of trains still use coal, but you get the energy that's required for that train to go.
Dr. Amber Krogsrud 11:18
Absolutely. I love using analogies to x, I think that can really help to understand what's happening with this entire world that's in our in our body that we aren't seeing on a daily basis.
Dr. Stephanie Gray 11:30
Let's talk a little bit about doses of those. So interestingly, recently, I've had a lot of patients with breast cancer and I know there have been several studies linking low Well, I would just say just demonstrating that patients with breast cancer tend to have lower levels of CO q 10. And it's so interesting in my practice, that when I test these patients, many of them are indeed low.
So I typically start patients on about 100 milligrams of CO q 10. Now if they're on medications, like you mentioned, like a static medication or blood pressure medications, diabetes medications, how I was trained and you can see Tell me what your thought process on this is, is to add another hundred milligrams for each of those drugs because that depletion is going to be worse. But the addition of each medication so some patients will put on 300 milligrams of CO q 10. Just monitoring blood pressure because I can, it's a healthy way to help lower blood pressure, but patients don't tolerate it, then we can back down on the dose. But that's typically what I'm recommending.
Dr. Amber Krogsrud 12:21
Yes, I usually start at 100 milligrams as well. And then, you know, contingent upon other medications that they're on. I think that that's Yeah, I completely agree with that protocol.
Dr. Stephanie Gray 12:31
Alpha lipoic acid, I also use as well, the I. The only downside that I find with that is it can drop blood glucose, not blood pressure, blood glucose. So that's actually great for patients with neuropathy and with diabetes, but that's one thing we need to monitor so all start patients 300 600 milligrams, sometimes get up to 1200.
Dr. Amber Krogsrud 12:51
Yeah. She started about 200 300 milligrams of alpha lipoic acid, yeah, but it because it works on the liver. It absolutely impacts blood glucose. Yeah, are cool. And then acetyl l carnitine. I usually will start about 500 milligrams. Yeah, twice a day once a day.
Dr. Stephanie Gray 13:11
Yeah. Awesome. We have a product called mitochondrial complex that is packed with all those antioxidants that I have I can't live without. It's a multivitamin that also has those. And when I was pregnant and breastfeeding, I couldn't take it because it helps with detox. And so I couldn't wait to be able to get back on it and I'm back on it. And I just I feel better. I just, I have less brain fog. My energy's better, clearly because it's fueling my mitochondria. And so I'm a big fan of Bose.
Dr. Amber Krogsrud 13:38
Yeah, that has really helped me to, I just remember how I felt graduating from medical school and undergrad, just 11 years of school do a lot terrifying, you know, in a negative way. And so, yeah, really supporting my mitochondrion when I learned about all this, I do feel Better mentally. Energy wise that I had, you know, reflecting back on what it was like graduating medical school has been really helpful for me as well. Yes, it's really good to hear.
Dr. Stephanie Gray 14:13
We're so blessed to have these tools. Yeah, that everyone does and that's why we're sharing them with others. Yes,
Dr. Amber Krogsrud 14:18
Dr. Stephanie Gray 14:23
Could you be missing out on magnesium if you aren't already taking magnesium you likely should be are deficient food sources caffeine consumption, stress and exercise, rob us of magnesium, which is an important cofactor for hundreds of processes in the body. It can calm your mind and ease your nerves to help you sleep at night and help reduce anxiety, PMS and headaches.
It can relax your muscles when you have cramps your bowels when you're constipated, and it's required for energy hormone production and vitamin D absorption. If you're interested in exploring more about how magnesium can help support you living a longer, healthier life and the exact type of magnesium supplement to look for, check out my blog post The Magnificent Seven Magnesium found at your longevity blueprint comm forward slash blog and use code magnesium for 10% off our magnesium keylite product at your longevity blueprint calm. Now let's get back to the episode.
Let's talk about a nutrient known as an ad that I've been just more recently utilizing in my practice. The I don't know if you went to a forum conference last December but there's a speaker, Christian from Quicksilver spoke on an ad. And I that reminded me Oh, I better start using this nutrient again because it kind of fell off my radar. But it is something that many of my patients are now asking me about and it also can help with mitochondria. So tell us more about an ad and how you use it.
Dr. Amber Krogsrud 15:51
Yeah, so any DD is one of these amazing molecules. It's a coenzyme. And we simply For mitochondrial function, so it's an oxidation reduction process, which is just a chemical reaction for anybody listening. But it's involved. Really in the energy generation process. We know that as you age, your energy levels decrease. And I've also had patients ask me, can we test your mid levels? And or mitochondrial function, there's some things we could do to maybe get a glimpse at mitochondrial function, but we can't actually like measure your blood level event ID or anything like that. Or you know,
Dr. Stephanie Gray 16:34
we can measure B to like just plain, you know, what not. Yeah, and we can measure mp3 right? Like niacin. Yes. But we can't measure it this specific form like this an ad we can measure niacin, but not this specific.
Dr. Amber Krogsrud 16:51
Yes, exactly. Yeah. Yeah. And so sad. We should say just what it means. It's Nikita mide and Danny dinucleotide so that's what we call it nav because nobody wants to say that. But really what nav does is it helps the brain cells to age well. And then we talked a lot about mitochondrial function in the frm module for peptides. And we talked about this molecule called PG c one alpha, so it's just a signaling molecule. But NPD controls the signaling of PGC, one alpha, and that actually protects the cells against oxidative stress that process so when we give extra an ad or support the body to make more of its on an ad, we're producing that pathway more and add more PG c one alpha, less oxidative stress, less cellular damage. So that's kind of the why behind an ad, and there's lots of different methods that you can administer nada so we can talk about what I do.
Yeah, I think I've used all of them on myself at this point that I know about. There's a there's an intra nasal form that you can actually it's very bioavailable to the brain crosses the blood brain barrier. And Alan's combined I think with B 12. And RG three, which is the red Korean ginseng, does it have to be compound and then is that a compounded nasal spray? It's a compound nasal spray TaylorMade used to carry it I don't know that they do anymore. But there's there's going to be places that other company pharmacies that make it but the intra nasal I actually have really found that to be helpful with brain function. I've I'm a morning coffee drinker and I, I will I have used that in place of it before and found that just energy brain function is supported through the morning through the day.
Dr. Stephanie Gray 18:58
But that Last, I mean, if you shoot it up your nose in the morning, how long do you think the effects are gonna last?
Dr. Amber Krogsrud 19:07
You know, a couple hours? Yeah, at least at least a couple hours. And of course the dose that you take intranasal is not the same that you would give IV or even topically, it's just kind of hard to dosa design. But for if it's very specific for brain for somebody who is having memory issues, or you know, early dementia like symptoms, using that form can be a little bit more specific to the brain, which could be great or even auto.
Yeah. I love that form. And then there's also so we have our IBS, which is kind of where a lot of people heard about an ad, and ad IVs. A lot of addiction centers. There's one in San Diego that I'm very familiar with. owner and they use an ad for addiction protocols for aging brains preventative using it for patients who do have a formal diagnosis of neurocognitive decline like dementia, Alzheimer's, Parkinson's, so lots of potential uses the nada IV. I'm sure you've had patients talk about the experience of the nada v. I familiar with the side effects. Are you talking about washing? Or are you okay? Yeah, flushing it a lot of times nausea. You know, they get it.
And I've experienced it the kind of this like your stomach slips, you know, feeling when you get an na da B and the solution to that is to slow the drip rate or to start a low dose. So when I give my patients na D IVs, and I give myself them, I usually start at 100 milligrams, sometimes 200 but usually I'll start at a pretty low dose. A lot of the therapeutic Ivy's that they're getting at addiction facilities are it's like a four hour drip fire. hundred milligrams and that's his stomach flipping IV, I mean, you will have to drop that really slow because you could feel pretty uneasy for that that period of time if you don't. So starting at a lower dose is great for most people.
And it's interesting because some people, some patients experience significant bursts of energy after that, and others will experience more fatigue. It could be due to some of the other things in the bag that help their detox pathways and they're detoxing a lot. But the overall effects of the NA D is to help them mitochondria. If they're really in a depleted state, they might actually feel a little bit more tired. Most people feel energized, but it's hard to know how someone might respond to their first an ad IV.
Dr. Stephanie Gray 21:49
So I don't know if you know the answer to this, but when I think of an ad, I think niacin, I think flushing. So would a patient who needs help with methylation would this Be contraindicated. And because many times for over methylation, we'll use niacin. So because of the concern that many patients have with mthfr variants that they need help with methylation, should we be cautious using an ad in those patients or not?
Dr. Amber Krogsrud 22:15
Yes, you know, I'm not 100% sure, because I don't, I'm not an expert in genetics, but I do believe that. Dr. Ben Lynch, is a naturopathic doctor and he talks a lot about methylation, and I think he actually has some content out about an ad and methylation. So
Dr. Stephanie Gray 22:34
speaking of genetics, there are genes because I have some of them that indicate an individual might likely benefit even more from from an ad. So that's also something that we can look into with determining you know, the best antioxidants are the best, I should say, the highest need for patients like if they should take an ad or not.
Dr. Amber Krogsrud 22:52
Yes, and I think that's really an important piece too is if we can get confirmation that's Gonna be more effective for them specifically, it's going to be more of an opt in where you know you can give it to a patient black and white this you need this molecule. Here's why. I think it's a it's easier to, to really give them that and have them continue taking it or sitting through an IV if that's what it takes. But
Dr. Stephanie Gray 23:19
the offer Ivy's at my practice, but we have not yet done any sort of high dose an ad so it's good to know about the flushing, I have a sublingual version here, sublingual zomo version, so that's all that I recommended to this point, but we may have to try the nasal spray or that IV so those are good.
Dr. Amber Krogsrud 23:37
There's one more so that we're sure that the sublingual I actually have not tried the sublingual, so I would love to hear your experience with the sublingual.
Dr. Stephanie Gray 23:45
Well, I personally haven't taken it because I was breastfeeding. I'm not done. But that's just the one that I've recommended in my practice, and only to a handful of patients who you know, they read about an ad and they were so convinced it's going to help. Sometimes I think there's a bit of Have a placebo because it shatters into that. But so far I've heard good things. And on one side effects, flushing. Yeah, I'm curious about that over the last route. Yeah.
Dr. Amber Krogsrud 24:12
So there's one more route and that's transdermal. And that's a patch that goes on the skin, actually, I'm feeling a little bit. I put one on two days ago. And the patch is, so they actually send you the mid fluid, this similar stuff to what you inject and there's a little absorptive pad that you put the nav fluid on, and then it's just a sticky, it's an ion transport.
So if you put just the straight fluid on your arm and just let you know, rubbed it in, nothing would happen. That's not bioavailable, so we've had to develop a way to actually get it to absorb well into the skin and so it's I do for racists, an ion transport system. And generally, I found that most people tolerate it pretty well. Like the only people who really shouldn't use the patch is somebody who has so it works through electrical conduction. So somebody the pacemaker, sure, you know, probably not a good individual, probably not in pregnancy, but really, most individuals respond well to Pash, and it's less expensive than an IV, it's less time consuming.
You don't have to go into a doctor's office. It's really a good option for many, many patients. I've had patients who are iram, alza, chronic fatigue, have a lot of benefit from the patches in combination with other treatments. LDN other things that we're doing to really support them too, so But yeah, there's so many ways to take an ad. It's amazing.
Dr. Stephanie Gray 25:57
Those wonderful, well, let's transition into talking about peptides. So, first for my audience, peptides, maybe what you're about to speak about maybe a different language. So let's break down what peptides are first and then we'll kind of talk about peptides for various things like mitochondrial function. So, what are peptides?
Dr. Amber Krogsrud 26:19
Yes. So, the analogy that I like to use something that everybody understands is, you know, when when you eat a piece of chicken or a piece of protein, I like to give the example of a piece of chicken. What your body does is it breaks it down through the digestive process. We have our stomach acid and all of our enzymes. Thanks again, Symes. But essentially, we have a protein in the chicken that breaks down to a peptide and a peptide is just a subunit. It's like a train.
So the train has many boxcars. All of those boxcars are amino acids. And then the small subunit is just a single amino acid. So we have the protein peptide, and then the amino acid, the small subunit. And so what peptides are, they're kind of that middle segment with lots of boxcars in a train, we can, you know, put together different combinations of those box cards or those amino acids. And what that does is it sends a different signal with different combinations. And so the way that peptides work is they work through cellular signaling.
We know that all of ourselves are like a planet think about Mars, and Mars has a bunch of docking stations on it, where spaceships can land and so this is the best, you know, easiest way to envision what's happening with a peptide is, you know, the, we inject or we take an oral form. There's lots of different forms of peptides, but it will bind to the cell, just like a spaceship, what on Mars and something would change inside the cell and You know, to promote a process to inhibit a process and a lot of cases talking about mitochondria. So we're supporting an ad, we're supporting the pathways for the mitochondria to protect itself, protect the cell.
So, peptides are just signaling molecules, they just send a signal. We know from lots of research, there's been research done on peptides in Russia since the 1970s, and 80s. We have research on peptides like a pet along with lengthen telomeres, produce help an individual to produce more of their own melatonin, which is really important as we age, not only for sleep, but anti inflammatory and immune effects. And so, we know these pathways, we know the pathway for hair loss for stem cells in the hair follicle and what's happening and so we can we can go in and we can peptides, like pgdbm, which is a peptide for that signals to stem cells in the hair follicle to wake up and still produce. There's all sorts of peptides that signal protective processes, you know, helping the mitochondria helping for collagen synthesis. There's literally a peptide for most every
for everything but they're wiktor they work through cellular signaling,
Dr. Stephanie Gray 29:31
in essence, so one main complaint that I have patients coming to see me as they want to lose weight of course and we want to optimize their thyroid and their sex hormones and get them on clean eating and help with reducing insulin resistance and detox the body. There are multiple steps in my you know, longevity blueprint that I walk patients through, but I think adding peptides is a whole nother layer that many patients have not yet been able to utilize. So can you speak To which peptides you use to help with I say weight loss, but more or less body composition change, specifically getting rid of fat in certain areas and then how those are administered if they're injections or topicals. speak a little bit to those peptides, the top ones that you use. I love
Dr. Amber Krogsrud 30:16
one of my favorite peptides and I work closely with a personal trainer in Hollywood, who refers a lot of women to me with this weight loss is their number one goal or body composition, they have to get in shape for you know, some event or thing that's going on. And so I've been asked this a lot and you know, had a lot of feedback on peptides and experiences from patients with them in my own experience, too.
So the the peptide combo, there's two peptides that I like to really Use kind of as a first line for and this is this is after all of the you know dietary lifestyle sleep stress cortisol hormones, you know we do that's first pillar and to me peptides are kind of next level it's like once we've looked at all of those and as much as possible helps to optimize the lifestyle pieces then it's like, okay, let's add in the peptides, sometimes adding in a peptide that helps deepen sleep, produce better energy helps someone it's a quick win, they get more energy to make those lifestyle changes.
So you know, it's a, it's a cat and mouse thing. Sometimes it actually helps to boost their energy, get them in a better mental emotional place. Increase the energy to make those changes but the two contents that I like to use are cjC, 1295 and ipamorelin. Those are just biochemical names that were given in the lab to these two peptides. One of them well both of them work on the pituitary. So the cjC 1295 is like the production so if you think about maybe like a target or a store and you have the actual store that's producing all of these boxes and then I Berlin is like the trucks that are delivering it to the body, that's the way that I like to think about it. So cjC increases production at Berlin is kind of the you know, shipping it out and making it available. Oh, growth hormone,
or just other farm, okay.
Yes, no growth hormone so
and they're working on the pituitary. What they're really doing is helping your body to make more of its own very different than nor to tropen You know, any sort of exotic growth hormone injections, which a lot of clinics do here in LA and around the country where they're administering the exoticness form. So not that they're not helping your body necessarily make more of its own. They're just injecting a separate source. Sure. And you can run into a lot of trouble doing that. In terms of side effects. You know, cardiac issues acromag like there's a lot, there's a ton of side effects, and there's a time and place to use some of those exoticness growth hormone supplementation, but for the average person, what we want to do is really just refine their body's ability to make more of it themselves. And this is not a lot of people are worried about cancer.
So one of the biggest questions around some of these peptides and increasing growth hormones It can increase IGF one. But it really, it's so transient. The way that peptides do it. It's trying we're trying to mimic the natural rhythm, which is what we try and do with bioidentical hormones to try and mimic that natural rhythm of what's happening in the body. And peptides are, you know, really, you can turn them by identical so it's really something that our body makes already, right. Like BPC 157. Are you familiar with that specific peptide?
Dr. Stephanie Gray 34:29
Is that still available though?
Dr. Amber Krogsrud 34:31
Yes, yes. Okay. could change soon. It just depends where you source it from. Yeah, I there's a reputable source that I have that's based out of LA and there's there's a couple places but there's also places where it's not available anymore. So there's a lot of changes FDA wise, with with peptides. Sure. Yes, unfortunately.
Dr. Stephanie Gray 34:54
Oh, yes. new landscape with peptides. For the listener that just means what used to be available, isn't it? Some of what used to be available is not still available. But practitioners like both of us are working to find some other solutions and alternatives for sure. I want to get this to hair loss real quick because I think for those listening, they may be interested in what they can do for their hair loss. So which peptides Do you use for hair loss and even some other modalities like micro needling or PRP or speak to that a little bit?
Dr. Amber Krogsrud 35:25
Oh, yeah, that's a huge topic. So I like to do I do like to do the micro needling so I have a micro needling pen at home we have one at the clinic and causing that kind of micro trauma to the area. We know that that compounds the results of peptides, when you combine the micro needling plus the peptides we get much better results so so people can apply the peptides topically or you there's one that you can inject for collagen synthesis the GH ACU but they're more effective. went on in topical way with the micro needling. So the ones that I love are this one called PTD dBm, which is a really long
they abbreviate it for a reason.
This is another one valproic acid, which is very commonly used, there's a phone that you can apply after micro needling. And then the other one that I've used myself both topically and injection is called gh kCu. So it's a copper peptide. And a lot of people when they when we talk about knee unders, throw the word peptides out, they think oh, the skin cream that I bought at Northshore that has peptides in it. So and it's or they think collagen peptides which is a supplement. similar idea but different, different thing. So the GH kCu I actually love that And really helps copper is really necessary for collagen synthesis and connective tissue but a lot of can really help with hair regrowth with healthy skin as we age. So it really it depends. Usually I'll start with the GH hkcu
and then micro needling
Unknown Speaker 37:21
Dr. Amber Krogsrud 37:22
or topically, yeah, you could do it. You could do this sub q injection at gh kCu. But I I just started topically. Sure. And then the XR person produces more of a systemic effect for women who really want to create healthy collagen systemically. But if we were looking local for hair, yes, topically valproic acid has been one of the more effective things that I learned about through a forum for hair loss topically as well combined with micro needling.
Dr. Stephanie Gray 37:54
Interesting, interesting. So for those listeners who want to know a lot more More about peptides, you actually have a free gift that probably is going to help. So you want to talk a little bit about that.
Dr. Amber Krogsrud 38:05
Yeah, definitely. So it's the pro peptide diet. And it really is a way of eating to help our body to regenerate and help our, you know, tissue or collagen in our skin or muscles to repair. Looking at it from a mitochondrial perspective, as well as you know, what's happening with the signaling and how can we shy of injecting peptides or using some of these things that you'd have to work with a doctor how you can really eat and live in a way that promotes you know, health of your tissues, diet, lifestyle, sleep redlight talk a lot about a lot of those things.
Dr. Stephanie Gray 38:48
We probably could talk for another hour but back on it any more peptides? Yes. So tell us what you think the average kind of cost of peptide there Be, may be for some patients that probably varies dramatically. But yeah, the slides are not cheap. They're
Dr. Amber Krogsrud 39:08
Yeah, yeah, they're not they're not cheap they are.
So, in LA, a lot of it's comparable to what a man might pay for testosterone therapy on a monthly basis like identical karma. Yep. Or for some women to they're on all three hormones. So sure it's in the range of three to 350 $400 a month, it depends on depends on the protocol. You know, like a pet Alon is a 10 day protocol, but you dose it really high. So it's kind of expensive for 10 days, but you don't do it every day all day. And then things like the cjC morale, and that's a usually about a three month on three month off. So it's not something that you're necessarily going to have to be on forever. But that one's about 300 to 350 a month. Sure, depending on you know, if you buy three months or one month or so, yeah, but it's but it's comparable to bioidenticals. And and at least in LA, maybe different around parts of the country. Sure, sure.
Dr. Stephanie Gray 40:14
Well tell us where listeners can find you and follow you on social media and learn more about what you have to offer.
Dr. Amber Krogsrud 40:20
Definitely, yeah, so they can find me on my Instagram, which is Dr. Do ctlr spelled out Amber. en de like North Dakota. That's my personal Instagram and then I have an Instagram just for peptides. And that's peptide RX. So just peptide and then our x. On Instagram, they can also look up a Facebook group for peptides where people can ask questions and I post a lot of PDFs and really helpful information about peptides. They can connect with me that way. I'm in the group they can reach out if they have questions about peptides that way and then My website is Dr. Amber and D. Calm and they can book an appointment, you know find out more about peptides there as well. So yeah, definitely happy to connect with anybody and talk about peptides and there's there needs to be more shared for consumers in that way. There's a lot for doctors, but I think putting out more content about peptides for patients is a focus of mine.
Dr. Stephanie Gray 41:30
Well, thank you so much. That was a wonderful, likely intro to many of my followers have put peptides on her. And there are so many again, we'll just we'll have to talk more in the future. That additional peptides, but thank you so much for sharing your knowledge or really wealth of knowledge with us on nutrients to support mitochondrial function as well as peptides. Thank you for your time being on the show today. I appreciate it. Thanks.
Well, wasn't she a wealth of knowledge on peptides? Wow. I hope you learned a lot about peptides for body composition changes like weight loss for hair growth and even brain power. I hope you learned about how important the mitochondria are and how you can incorporate na D into your supplement routine. I'll be sure to be incorporating more peptides into my practice. And don't worry, I'm going to be bringing on more speakers to further that peptide discussion. Be sure to check out my book your longevity blueprint. And if you aren't much of a reader, you're in luck. You can now take my course online where I walk you through each chapter in the book.
Plus for a limited time Not only is the course 50% off, but you also get your first consult with me for free. Check this offer out at your longevity blueprint calm and click the course tab. One of the biggest things you can do to support the show and help us reach more listeners is to subscribe to the show. And leave us a rating and review on Apple podcasts or wherever you listen. I read all the reviews and would truly love to hear your suggestions for show topics, guests or how you're applying what you've learned on the show to create your own longevity blueprint. podcast is produced by the team at counterweight creative. As always, thanks so much for listening and remember, wellness is waiting.
The information provided in this podcast is educational. No information provided should be considered to be or used as a substitute for medical advice, diagnosis or treatment. Always consult with your personal medical authority.
Transcribed by https://otter.ai
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